khavaigunya

A weak or defective space within a tissue or organ where a pathological condition is likely to begin; a potential site of relocation.

A weak or defective space in the body typically caused by past injury, illness, trauma, or familial genetic patterns; khavaigunyas are especially vulnerable to frequent or chronic imbalance because they tend to attract ama and excesses in the doshas.

Source: http://www.banyanbotanicals.com/info/ayurvedic-living/learning-ayurveda/glossary-of-ayurvedic-terms/